Biltricide (praziquantel) is an anthelmintic, or anti-worm, medication used to treat infections caused by Schistosoma worms, which enter the body through skin that has come into contact with contaminated water. Schistosoma worms are found in Africa, South America, Middle Eastern countries, the Caribbean, and parts of Asia. Biltricide is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. Biltricide (praziquantel) increases permeability of membranes of cells of helminths for Ca2+, it causes the generalized reduction of muscles passing into the persistent paralysis leading to death of helminths.